声明：本专栏主要对生命科学领域的一些期刊文章标题进行翻译，所有内容均由本人手工整理翻译。由于本人专业为生物分析相关，其他领域如果出现翻译错误请谅解。
1.Rapid cloning of antigen-specific T-cell receptors by leveraging the cis activation of T cells.
通过利用T细胞的顺式激活来快速克隆抗原特异性T细胞受体。
2.Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker.
通过肿瘤蛋白酶可切割接头将白介素12与其受体结构融合来掩盖白介素12的免疫毒性。
3.CAR T cells expressing a bacterial virulence factor trigger potent bystander antitumour responses in solid cancers.
表达细菌毒力因子的CAR T细胞会引发有效的旁观者抗肿瘤反应。
4.Synthetic libraries of immune cells displaying a diverse repertoire of chimaeric antigen receptors as a potent cancer immunotherapy.
免疫细胞的合成库表现出多种嵌合抗原受体库，作为一种有效的癌症免疫疗法。
5.Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains.
通过细胞内结构域的条形码图库来筛选CD19特异性嵌合抗原受体，并具有增强的信号传导。
6.Glucosylated nanoparticles for the oral delivery of antibiotics to the proximal small intestine protect mice from gut dysbiosis.
用于将抗生素口服递送至近端小肠的糖基化纳米颗粒可保护小鼠免受肠道菌群失调。
7.Genetically engineered and enucleated human mesenchymal stromal cells for the targeted delivery of therapeutics to diseased tissue.
基因工程和灌注的人间质基质细胞，用于靶向疗法向患病组织的靶向递送。
8.Antigen-bearing outer membrane vesicles as tumour vaccines produced in situ by ingested genetically engineered bacteria.
携带抗原的外膜囊泡作为肿瘤疫苗由摄入的基因工程细菌原位产生。
9.An engineered live biotherapeutic for the prevention of antibiotic-induced dysbiosis.
一种设计的实时生物治疗，可预防抗生素诱导的营养不良。
1.Simplified Cas13-based assays for the fast identification of SARS-CoV-2 and its variants.
简化了基于CAS13的测定，用于快速识别SARS-COV-2及其变体。
2.Rapid detection of SARS-CoV-2 RNA in saliva via Cas13.
通过CAS13快速检测唾液中SARS-COV-2 RNA。
3.A paper-based assay for the colorimetric detection of SARS-CoV-2 variants at single-nucleotide resolution.
一种以单核苷酸分辨率比色检测 SARS-CoV-2 变体的纸基分析。
4.A lab-on-a-chip for the concurrent electrochemical detection of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in saliva and plasma.
用于唾液和血浆中SARS-CoV-2 RNA和抗SARS-CoV-2抗体的同时电化学检测的实验室芯片。
5.Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples.
通过光学检测血液样本细胞外囊泡的两个毒力因子来诊断小儿结核病。
6.Unbiased discovery of autoantibodies associated with severe COVID-19 via genome-scale self-assembled DNA-barcoded protein libraries.
通过基因组规模的自组装DNA条形码蛋白文库公正地发现与严重COVID-19相关的自身抗体。
7.Droplet-microfluidics-assisted sequencing of HIV proviruses and their integration sites in cells from people on antiretroviral therapy.
液滴微流体辅助测序HIV前病毒及其在接受抗逆转录病毒治疗的人的细胞中的整合位点。
1.Non-invasive monitoring of blood oxygenation in human placentas via concurrent diffuse optical spectroscopy and ultrasound imaging.
通过并发弥漫性光谱和超声成像对人胎盘中的血液氧合的无创监测。
2.Multiscale optical and optoacoustic imaging of amyloid-β deposits in mice.
小鼠淀粉样蛋白β沉积物的多尺度光学和光声成像。
3.A nanoparticle probe for the imaging of autophagic flux in live mice via magnetic resonance and near-infrared fluorescence.
通过磁共振和近红外荧光对活小鼠中自噬通量成像的纳米颗粒探针。
4.Revealing nanostructures in brain tissue via protein decrowding by iterative expansion microscopy.
利用迭代扩展显微镜，通过蛋白质去拥挤揭示脑组织中的纳米结构。
5.Spatially resolved in vivo imaging of inflammation-associated mRNA via enzymatic fluorescence amplification in a molecular beacon.
通过酶促荧光扩增在分子信标中与炎症相关的mRNA的体内成像。
1.Low-cost gastrointestinal manometry via silicone–liquid-metal pressure transducers resembling a quipu.
通过类似于奇普的硅胶-液态金属压力传感器进行低成本胃肠测压。
2.Collagen-binding peptides for the enhanced imaging, lubrication and regeneration of osteoarthritic articular cartilage.
胶原结合肽，用于增强骨关节炎软骨的成像，润滑和再生。
3.A strain-programmed patch for the healing of diabetic wounds.
用于治愈糖尿病伤口的应变程序贴片。
4.A soft robotic sleeve mimicking the haemodynamics and biomechanics of left ventricular pressure overload and aortic stenosis.
一个软机器人套筒，模仿左心室压力超负荷和主动脉狭窄的血液动力学和生物力学。
5.Brachytherapy via a depot of biopolymer-bound 131I synergizes with nanoparticle paclitaxel in therapy-resistant pancreatic tumours.
通过生物聚合物结合的131I库的近距离放射治疗与纳米颗粒紫杉醇在治疗耐药的胰腺肿瘤中协同作用。
6.Enhanced tendon healing by a tough hydrogel with an adhesive side and high drug-loading capacity.
通过具有粘性面和高载药能力的坚韧水凝胶增强肌腱愈合。
7.A potent antibiotic-loaded bone-cement implant against staphylococcal bone infections.
一种有效的载有抗生素的骨水泥植入物，可抵抗葡萄球菌性骨感染。
1.An off-the-shelf otoacoustic-emission probe for hearing screening via a smartphone.
一种现成的耳声发射探头，用于通过智能手机进行听力筛查。。
2.An integrated wearable microneedle array for the continuous monitoring of multiple biomarkers in interstitial fluid.
一个集成可穿戴的微对阵列，用于连续监测间质液中多个生物标志物。
3.A wearable electrochemical biosensor for the monitoring of metabolites and nutrients.
可穿戴的电化学生物传感器，用于监测代谢物和营养素。
4.Nutritional deficiency in an intestine-on-a-chip recapitulates injury hallmarks associated with environmental enteric dysfunction.
肠道芯片中的营养缺乏概括了与环境肠道功能障碍相关的损伤特征。
5.A humanized minipig model for the toxicological testing of therapeutic recombinant antibodies.
用于治疗重组抗体的毒理学测试的人性化小型猪模型。
6.Variants of the adeno-associated virus serotype 9 with enhanced penetration of the blood–brain barrier in rodents and primates.
腺相关病毒血清型9的变体在啮齿动物和灵长类动物中具有增强的血脑屏障穿透能力。
7.Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors.
通过与大小优化基因组编码紧凑型腺嘌呤碱基编辑器的单个腺相关病毒进行有效的体内基础编辑。
8.Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells.
T细胞衍生诱导的多能干细胞的T细胞阴性CD8αβ阳性CAR T细胞的产生。
9.Mapping and targeted viral activation of pancreatic nerves in mice reveal their roles in the regulation of glucose metabolism.
小鼠胰腺神经的映射和靶向病毒激活揭示了它们在调节葡萄糖代谢中的作用。
1.Detection of signs of disease in external photographs of the eyes via deep learning.
通过深度学习，在眼睛外部照片中发现疾病迹象。
2.A cost-aware framework for the development of AI models for healthcare applications.
用于开发用于医疗保健应用的AI模型的成本感知框架。
3.Expert-level detection of pathologies from unannotated chest X-ray images via self-supervised learning.
专家级别通过自我监督学习从未注释的胸部X射线图像中发现病理。
4.A deep-learning model for transforming the style of tissue images from cryosectioned to formalin-fixed and paraffin-embedded.
一种深入学习模型，用于将组织图像的风格从冷冻切片变成福尔马林固定和石蜡包裹的模型。
5.Fast and scalable search of whole-slide images via self-supervised deep learning.
通过自监督深度学习快速且可扩展地搜索整张幻灯片图像。
6.Graph deep learning for the characterization of tumour microenvironments from spatial protein profiles in tissue specimens.