声明：本专栏主要对生命科学领域的一些期刊文章标题进行翻译，所有内容均由本人手工整理翻译。由于本人专业为生物分析相关，其他领域如果出现翻译错误请谅解。
1.Identification of tumor antigens with immunopeptidomics.
用免疫肽学鉴定肿瘤抗原。
2.CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells.
斑马鱼和原代人细胞中的核糖核蛋白复合物的CRISPR Prime编辑。
3.Compact RNA editors with small Cas13 proteins.
带有小CAS13蛋白的紧凑型RNA编辑器。
4.Wireless closed-loop optogenetics across the entire dorsoventral spinal cord in mice.
小鼠整个背腹脊髓的无线闭环光遗传学。
5.Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer.
未注释的蛋白质在癌症中扩展了MHC-I限制的免疫肽组。
6.Precise genomic deletions using paired prime editing.
使用配对的主要编辑精确的基因组缺失。
7.Deletion and replacement of long genomic sequences using prime editing.
使用主要编辑删除和替换长基因组序列。
8.Chromatin Velocity reveals epigenetic dynamics by single-cell profiling of heterochromatin and euchromatin.
染色质速度通过异染色质和常染色质的单细胞分析揭示表观遗传动力学。
9.Differential abundance testing on single-cell data using k-nearest neighbor graphs.
使用K-Nearest邻居图对单细胞数据进行差异丰度测试。
10.Multiscale and integrative single-cell Hi-C analysis with Higashi.
使用Higashi的多尺度和综合单细胞HI-C分析。
11.A small and highly sensitive red/far-red optogenetic switch for applications in mammals.
用于哺乳动物应用的小型且高度敏感的红外/远红外光遗传学开关。
1.Spatial components of molecular tissue biology.
分子组织生物学的空间成分。
2.Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children.
上呼吸道的预激活的抗病毒先天免疫控制儿童的早期SARS-CoV-2感染。
3.Direct targeting of amplified gene loci for proapoptotic anticancer therapy.
直接靶向放大基因位点进行促凋亡抗癌治疗。
4.Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale.
工业中试规模气体发酵法负碳生产丙酮和异丙醇。
5.Cell segmentation in imaging-based spatial transcriptomics.
基于成像的空间转录组学中的细胞分割。
6.Co-varying neighborhood analysis identifies cell populations associated with phenotypes of interest from single-cell transcriptomics.
共同的邻域分析确定了与单细胞转录组学感兴趣的表型相关的细胞群体。
7.Highly-multiplexed volumetric mapping with Raman dye imaging and tissue clearing.
用拉曼染料成像和组织清除进行高度多形的体积映射。
8.Single-cell profiling of proteins and chromatin accessibility using PHAGE-ATAC.
使用Phage-ATAC的蛋白质和染色质可及性的单细胞分析。
9.High-throughput functional characterization of protein phosphorylation sites in yeast.
酵母中蛋白质磷酸化位点的高通量功能表征。
10.Functional single-cell genomics of human cytomegalovirus infection.
人类巨细胞病毒感染的功能性单细胞基因组学。
11.Engineered pegRNAs improve prime editing efficiency.
工程化pegRNAs提高了主要编辑效率。
12.High-confidence structural annotation of metabolites absent from spectral libraries.
光谱文库中没有代谢物的高置信度结构注释。
13.Population genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement.
节节山羊草的种群基因组分析确定了改善面包小麦的靶标。
1.Super-resolved spatial transcriptomics by deep data fusion.
通过深度数据融合构建超分辨的空间转录组学。
2.Remote smartphone monitoring of Parkinson’s disease and individual response to therapy.
远程智能手机监测帕金森氏病和个人对治疗的反应。
3.T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes.
靶向TdT的T细胞杀死白血病淋巴母细胞，同时保留正常淋巴细胞。
4.Improved prediction of immune checkpoint blockade efficacy across multiple cancer types.
改善了多种癌症类型的免疫检查点阻断功效的预测。
5.Fast and accurate metagenotyping of the human gut microbiome with GT-Pro.
用GT-Pro对人肠道微生物组的快速准确的宏基因分型。
6.Robust decomposition of cell type mixtures in spatial transcriptomics.
强大分解空间转录组学中细胞类型混合物。
7.Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data.
通过整合大量和单细胞测序数据来识别与表型相关的亚群。
8.RNA-responsive elements for eukaryotic translational control.
用于真核翻译控制的RNA响应元素。
9.Locus-specific expression of transposable elements in single cells with CELLO-seq.
使用CELLO-seq在单细胞中转座因子的位点特异性表达。
10.Whole-cell segmentation of tissue images with human-level performance using large-scale data annotation and deep learning.
使用大规模数据注释和深度学习对具有人类性能的组织图像进行全细胞分割。
11.Deep distributed computing to reconstruct extremely large lineage trees.
深层分布式计算以重建极大的谱系树。
12.Personalized phosphoproteomics identifies functional signaling.
个性化的磷蛋白组学鉴定功能信号传导。
13.Inferring gene expression from cell-free DNA fragmentation profiles.
从无细胞DNA片段化轮廓中推断基因表达。
14.Genetically encoded photo-switchable molecular sensors for optoacoustic and super-resolution imaging.
用于光声和超分辨率成像的基因编码光开关分子传感器。
15.Sparse deconvolution improves the resolution of live-cell super-resolution fluorescence microscopy.
稀疏的反卷积改善了活细胞超分辨率荧光显微镜的分辨率。
1.Sensitive identification of neoantigens and cognate TCRs in human solid tumors.
对人类实体瘤中新抗原和同源TCR的灵敏鉴定。
2.Cell2location maps fine-grained cell types in spatial transcriptomics.
Cell2Location在空间转录组学中映射细粒度细胞类型。
3.Curated variation benchmarks for challenging medically relevant autosomal genes.
用于挑战医学相关常染色体基因的精选变异基准。
4.Multiscale PHATE identifies multimodal signatures of COVID-19.
多尺度PHATE标识了COVID-19的多模式特征。
5.A knowledge graph to interpret clinical proteomics data.
解释临床蛋白质组学数据的知识图。
6.scJoint integrates atlas-scale single-cell RNA-seq and ATAC-seq data with transfer learning.
scJoint通过转移学习整合了地图尺度的单细胞RNA-seq和ATAC-Seq数据。
7.Generating lineage-resolved, complete metagenome-assembled genomes from complex microbial communities.
从复杂的微生物群落产生谱系分辨、完整的元基因组组装基因组。
8.Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues.
在人体组织中高时空分辨率下进行细胞谱系追踪的波动甲基化时钟。
9.Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing.
有Twin Prime编辑的可编程删除、替换、集成和反转大型DNA序列。
10.Partitioning RNAs by length improves transcriptome reconstruction from short-read RNA-seq data.
按长度分配RNAs可改善从短读RNA-seq数据中的转录组重建。
11.Engineering the amoeba Dictyostelium discoideum for biosynthesis of a cannabinoid precursor and other polyketides.
改造变形虫盘基网柄菌以生物合成大麻素前体和其他聚酮化合物。
12.CLUSTER guide RNAs enable precise and efficient RNA editing with endogenous ADAR enzymes in vivo.
CLUSTER指导RNAs可以使用体内内源性ADAR酶进行精确有效的RNA编辑。
13.Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors.
用于发现和表征KRAS抑制剂的构型锁定抗体。
14.Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins.
使用工程化光可切换RNA结合蛋白对RNA功能和代谢的光遗传控制。
15.A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo.
用于体内内源性大麻素动力学的空间分辨成像的荧光传感器。
1.The clinical progress of mRNA vaccines and immunotherapies.
mRNA疫苗和免疫疗法的临床进展。
2.Cell types of origin of the cell-free transcriptome.
无细胞转录组起源的细胞类型。
3.Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.
用于癌症相关单核苷酸变异的高通量工程和功能分析的碱基编辑传感器库。
4.High-throughput functional evaluation of human cancer-associated mutations using base editors.
使用碱基编辑器对人类癌症相关突变进行高通量功能评估。
5.Saturation variant interpretation using CRISPR prime editing.
使用CRISPR Prime编辑的饱和变量解释。
6.Massively parallel phenotyping of coding variants in cancer with Perturb-seq.
使用Perturb-seq进行癌症编码变异的大规模平行表型分析。
7.A humanized mouse model of chronic COVID-19.
慢性COVID-19的人源化小鼠模型。
8.Identification of antimicrobial peptides from the human gut microbiome using deep learning.
使用深度学习从人肠道微生物组中鉴定抗菌肽。
9.Using deep learning to annotate the protein universe.
使用深度学习来注释蛋白质宇宙。
10.Efficient in vitro and in vivo RNA editing via recruitment of endogenous ADARs using circular guide RNAs.
通过使用圆形向导RNAs募集内源性ADAR，可以在体外和体内进行效率的RNA编辑。
11.Engineered circular ADAR-recruiting RNAs increase the efficiency and fidelity of RNA editing in vitro and in vivo.
工程化的环状ADAR募集RNA提高了体外和体内RNA编辑的效率和保真度。
12.Development of spirulina for the manufacture and oral delivery of protein therapeutics.
开发用于制造和口服递送蛋白质疗法的螺旋藻。
13.Imaging of innate immunity activation in vivo with a redox-tuned PET reporter.
使用氧化还原调谐PET报告器对体内先天免疫激活进行成像。